1. Which MDR organism is the cause of most antibiotic-resistant deaths?

2. Multi-drug resistant P. aeruginosa, ESBL-producing Enterobacteriaceae, CRE, VRE are associated with which type of infection?

3. By what mechanism does resistance develop in the fluoroquinolones?

4. Changes in cell surface adaption leads to resistance to which antibiotics?

5. What resistance mechanism prevents polymyxin antibiotics from binding to their target site of action?

6. How does relebactam work in the combination agent imipenem/cilastatin/relebactam?

7. Which recently approved antibiotic is recommended as an alternative treatment for CRE and MDR-Pa infections?

8. Which recently approved antibiotic is recommended as a first-line option for CRE and MDR-Pa infections?

9. Which aspect of the core components of an antimicrobial stewardship program are especially well-suited for pharmacist oversight?

10. Bacterial co-infections occur in most patients hospitalized with COVID-19.

11. What antibiotic would you empirically start as you await the final blood and urine culture results? CASE STUDY

12. Which antibiotic agent would you avoid? CASE STUDY

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