1. In the 2018 American College of Cardiology (ACC) Expert Consensus Decision Pathway on Novel Therapies for Cardiovascular Risk Reduction in Patients with Type 2 Diabetes (T2D) and Atherosclerotic Cardiovascular Disease (ASCVD), the ACC proposed 4 “opportunities” in which clinicians may consider starting a glucose-lowering agent with demonstrated cardiovascular benefit. Which of the following is NOT representative of the recommendations made by ACC?

2. According to the 2020 American Diabetes Association (ADA) Standards of Medical Care in Diabetes, which of the following should be considered an indicator of high risk for atherosclerotic cardiovascular disease (ASCVD)?

3. An agent from which of the following medication classes is preferred in the 2020 American Diabetes Association (ADA) Standards of Care for use in patients with clinically predominant chronic kidney disease (CKD)?

4. Which of the following is NOT a scenario in which the 2020 American Diabetes Association (ADA) Standards of Medical Care in Diabetes recommend consideration of a glucagon-like peptide-1 receptor agonist (GLP-1 RA) for use in patients with type 2 diabetes?

5. The 2020 American Diabetes Association (ADA) Standards of Medical Care in Diabetes recommend which of the following be considered as the first injectable agent in most patients to meet individualized A1C goals?

6. Which of the following is a mechanism of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in the setting of type 2 diabetes (T2D) that results in glucose lowering and reduction in body weight?

7. Which of the following glucagon-like peptide-1 receptor agonists (GLP-1 RAs) is administered subcutaneously once daily?

8. You are considering recommending the fixed-ratio combination (FRC) product insulin degludec/liraglutide for a patient with type 2 diabetes. What is the maximum number of insulin units that can be administered in a single injection with this product?

9. TL is a patient with type 2 diabetes (T2D) and established atherosclerotic cardiovascular disease (ASCVD). His primary care provider would like to start him on a glucagon-like peptide-1 receptor agonist (GLP-1 RA) and has asked if any of the currently available agents carries an indication to reduce the risk of major adverse cardiovascular events (MACE) in adults with T2D and established cardiovascular disease. Which of the following agents currently carries such an indication?

10. Which of the following is TRUE regarding the recommended administration instructions for oral semaglutide?

Evaluation Questions

11. How confident are in your treatment choice for patient TL in question #9:

12. How often do you incorporate the following into your clinical practice? Review current and emerging treatment options for patients with type 2 diabetes mellitus and established atherosclerotic cardiovascular disease

13. Develop treatment plans based on individual patient cardiovascular and renal needs, independent of A1c levels

14. Collaborate with providers about adopting a patient-centered approach considering cardiovascular comorbidities, hypoglycemia risk, impact on weight, cost, risk for side effects, and patient preferences

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