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1. Which of the following is NOT one of the unique properties of nanoparticles used in medical applications?

A. Particle size range and geometric shape of nanoparticles B. Porosity and overall surface area C. Core temperature-dependent aggregation D. Size-dependent dissolution E. Unsure

2. Which of the following is a key clinical advantage of lipid-based nanomedicines?

A. Lowering aqueous solubility to enhance oral absorption B. Enhanced intracellular uptake/membrane permeability C. Increased volume of distribution D. Higher administered dose is required to achieve sufficient local concentration at diseased tissue/organ E. Unsure

3. Select the correct statement below that describes the main advantage of adding polyethylene glycol (PEG) chains onto liposomal doxorubicin:

A. Better complexation between drug molecules and nanocarrier B. Increased loading capacity of nanocarrier for doxorubicin C. Increases the absolute bioavailability of the liposomal drug by multiple folds D. Increasing the circulation half-life of the nanomedicine E. Unsure

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