1. You are concerned that Jim may be frail. To determine his risk for frailty, which of the following should you ask him about during your clinical interview?

2. You determine that Jim is frail. According to guidelines, how frequently should you perform a frailty assessment in the future?

3. A 65-year-old female, Yvonne, who has been living with HIV for 30 years presents for routine blood work and follow-up. She has type 2 diabetes (T2D), which is managed with metformin 1000 mg twice daily, omeprazole 20 mg before breakfast, semaglutide 1 mg injection weekly, and canagliflozin 100 mg daily. She also has hypercholesterolemia, which is managed with atorvastatin 20 mg daily. Her antiretroviral therapy (ART) regimen includes darunavir/cobicistat (DRV/c) and tenofovir disoproxil fumarate/emtricitabine (TDF/FTC). She also takes omeprazole, oxybutynin, an adult multivitamin, calcium, vitamin D, antacids as needed, and a pill to help with sleep. Which of Yvonne's medications is most likely to lead to drug-drug interactions?

4. On discussing her medications with her, Yvonne notes that she frequently forgets to take “some of” her medications. Which of the following changes are options to improve her adherence?

5. Which of the following of Yvonne's medications would be most appropriate to consider deprescribing?

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