1. Fluoroquinolones can develop drug resistance by which mechanism?

2. Porin channel loss is the resistance mechanism for which class of antibiotics?

3. Bacteria that develop resistance vie efflux pumps impact the use of which antibiotics?

4. Which of the following are mutations in which cellular component create resistance to polymyxins?

5. Eravacycline would not be an appropriate option for patients with which type of infection?

6. Ceftolozane/tazobactam is a useful treatment option for which type of MDR infection?

7. Which susceptibilities tests are options to request for a 75-year-old female, with a history of type 2 diabetes mellitus and renal transplant, who presents with fever, abdominal pain and jaundice? A month ago, she was hospitalized with kidney stones and underwent lithotripsy at which time she had an indwelling catheter placed temporarily and received a broad-spectrum cephalosporin.

8. Plazomicin's spectrum of activity include which bacteria?

9. Ceftazidime/avibactam is approved for which of the following indications?

10. Which of the following interventions has been found LESS effective as part of an antimicrobial stewardship program?

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