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1. The four cardinal clinical features of PD include all of the following EXCEPT:

A. Resting tremor B. Bradykinesia C. Rigidity (cogwheeling) D. Excessive sweating

2. Which of the following symptoms do you think offers the most compelling evidence of premotor Parkinson's disease?

A. Rapid eye movement (REM) sleep behavior disorder (RBD) B. Constipation C. Olfactory dysfunction (hyposmia) D. All of the above

3. Recent evidence suggests all dopamine agonists may cause sudden onset sleep and impulse control disorders.

A. True B. False

4. According to the 056 study and CALM-PD trial, initial treatment with a dopamine agonist (ropinirole or pramipexole) delayed the onset of which of the following symptoms when compared to treatment with levodopa alone?

A. motor fluctuations B. dyskinesias C. hallucinations D. A and B

5. Based on data from the TEMPO and ADAGIO trials, do you believe Parkinson's disease patients may benefit from treatment being commenced immediately on diagnosis rather than waiting for functional disability to develop?

A. Yes B. No

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