Improving Outcomes with Novel Approaches in von Hippel-Lindau Disease: An Expert Review of Emerging Pharmacotherapeutic Strategies (an Interactive Monograph)

Jointly provided by Postgraduate Healthcare Education, LLC (PHE) and Postgraduate Institute for Medicine (PIM).

This activity is supported by an independent educational grant from Merck & Co., Inc.

FACULTY

Kirollos S. Hanna, PharmD, BCPS, BCOP, FACCC
Director of Pharmacy | Minnesota Oncology
St. Paul, MN
Assistant Professor of Pharmacy | Mayo Clinic College of Medicine
Rochester, MN

Nancy P. Moldawer, RN, MSN
Clinical Research Nurse—GU Medical Oncology
Clinical Cancer Trials Office
Cedars-Sinai Medical Center
Los Angeles, CA

FINANCIAL DISCLOSURE

Dr. Hanna has disclosed that he has received honoraria for non-CME activities Beigene, BMS, Exelixis, and Seagen.

Dr. Moldawer has disclosed that she has served on a speaker’s bureau for Exelixis.

The clinical reviewer, Lisa Holle, PharmD, BCOP, FHOPA has no actual or potential conflicts of interest in relation to this program.

The medical writer, Thomas Mitchell, has no actual or potential conflicts of interest in relation to this program.

Susanne Kwas, MSHF, BSN, RN, Robin Soboti, RPh, and Susan R. Grady, MSN, RN as well as the planners, managers, and other individuals, not previously disclosed, who are in a position to control the content of Postgraduate Healthcare Education (PHE) continuing education (CE) activities hereby state that they have no relevant conflicts of interest and no financial relationships or relationships to products or devices during the past 12 months to disclose in relation to this activity. PHE is committed to providing participants with a quality learning experience and to improve clinical outcomes without promoting the financial interests of a proprietary business.

The PIM planners and others have nothing to disclose.

Postgraduate Institute for Medicine (PIM) requires faculty, planners, and others in control of educational content to disclose all their financial relationships with ineligible companies. All identified conflicts of interest (COI) are thoroughly vetted and mitigated according to PIM policy.  PIM is committed to providing its learners with high quality accredited continuing education activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

All relevant financial relationships have been mitigated.

ACCREDITATION STATEMENTS

PHARMACY
Postgraduate Healthcare Education, LLC is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.
UAN: 0430-9999-24-078-H01-P
Credits: 2.0 hour (0.2 ceu)

Type of Activity: Application
Media: Internet

Fee Information: This activity is FREE. There is no fee for this educational activity.
Estimated time to complete activity: 120 minutes

Joint Accreditation Statement

In support of improving patient care, this activity has been planned and implemented by the Postgraduate Institute for Medicine and Postgraduate Healthcare Education. Postgraduate Institute for Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Continuing Nursing Education

The maximum number of hours awarded for this Continuing Nursing Education activity is 2.0 contact hours. Designated for 1.5 contact hours of pharmacotherapy credit for Advanced Practice Registered Nurses.

Published

September 27, 2024

Expires

March 27, 2025

TARGET AUDIENCE

This accredited activity has been designed for Oncology Pharmacists and Nurses.

HOW TO OBTAIN CREDIT

Participants must 1) read the learning objectives and faculty disclosures; 2) view the educational activity; and 3) complete the posttest and evaluation form directly after the activity within a maximum of 60 days of participating in the activity. To answer the questions, click on your selected choice for each answer then proceed to the next question. Once completed, click on the Grade Exam button at the bottom of the page. Your posttest will automatically be graded. If you successfully complete the posttest (score of 70% or higher), your statement of participation will be made available immediately. Click on the View Statement of Participation link and print the statement for your records. If you receive a score lower than 70%, you will receive a message notifying you that you did not pass the posttest. You will have 2 opportunities to pass the posttest. To receive Credit, you must provide your date of birth and NABP number. All Credit information will be uploaded into CPE monitor within 30 days.

Goal

The goal of this educational activity is to equip and empower oncology pharmacists and nurses with the knowledge, confidence, competence, and tools/resources necessary to recognize clinical hallmarks of VHL and serve vital patient-facing roles across the multidisciplinary treatment continuum, including the safe, effective, and patient-centric implementation of novel pharmacotherapeutics for management of VHL-associated tumors.

LEARNING OBJECTIVES

Upon completion of this program, participants should be better able to:

• Review hallmark clinical manifestations, diagnostic criteria, and expert consensus best practices for active surveillance of von Hippel-Lindau (VHL) disease across the patient lifespan.
  
• Evaluate the clinical trial evidence in support of novel systemic therapy approaches to treating VHL-associated tumors, highlighting regulatory milestones and the paradigmatic placement of approved agents.
  
• Design individualized, data-driven treatment plans for patients with VHL-associated tumors, with a focus on patient selection and management of treatment-related adverse events.

REQUIRED COMPUTER HARDWARE/SOFTWARE

Please ensure the computer system you plan to use meets the following minimum requirements:

• Operating System: Windows 98 or higher & Macintosh 2.2 or higher
• Internet Browser (Mac & Windows): Internet Explorer 6.0 or higher, Google Chrome, Safari 5.0.6 or higher, Firefox 3.0.3 or higher, & Opera 5 or higher
• Broadband Internet connection: Cable, High-speed DSL & any other medium that is internet accessible
• Peripherals: Computer speakers or headphones
• Monitor Screen Resolution: 320 x 480 or higher
• Media Viewing Requirements: Adobe Reader, Microsoft PowerPoint, Flash Player & HTML5

Disclosure of Unlabeled Use and Disclaimer

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of Postgraduate Healthcare Education, LLC, Postgraduate Institute for Medicine (PIM), or Merck & Co., Inc. Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients' conditions, and possible contraindications on dangers in use, (review of any applicable manufacturer's product information) and comparison with recommendations of other authorities.

The author, sponsor, and publisher of this continuing education activity have made all reasonable efforts to ensure that all information contained herein is accurate in accordance with the latest available scientific knowledge at the time of acceptance for publication. However, because information regarding drugs (their administration, dosages, contraindications, adverse reactions, interactions, special warnings, precautions, etc.) is subject to constant change, the reader is advised to check the manufacturer's package insert for information concerning recommended dosages and potential problems and cautions prior to dispensing or administering the drug. Special precautions should be taken when a drug is new, or highly toxic, or is unfamiliar to the dispenser or administrant. This educational activity may contain discussion of published and/or investigational uses of agents that are not approved by the U.S. Food and Drug Administration (FDA). Neither the publisher nor sponsor promotes the use of any agent outside of approved labeling. Statements made in this activity have not been evaluated by the FDA.