Curbside Consults: Real-Life Case Studies to Simplify HIV PrEP Implementation

This continuing medical education activity is provided by

This educational activity is supported by an independent educational grant from ViiV Healthcare. ViiV Healthcare was not involved in the development of content or selection of faculty for this educational activity.

Activity Description

HIV attacks the immune system and, if left untreated, can lead to acquired immunodeficiency syndrome. Pre-exposure prophylaxis (PrEP) is highly effective in preventing HIV transmission, but its uptake remains low due to gaps in clinician knowledge and barriers in openly discussing PrEP with patients. Updated guidelines from the US Centers for Disease Control and Prevention (CDC) recommend offering PrEP to all sexually active individuals and those at substantial risk of HIV, including individuals with partners of unknown HIV status or who have a history of sexually transmitted infections. Various PrEP options exist, including once-daily oral tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC), once-daily oral tenofovir alafenamide (TAF)/FTC, and the long-acting injectable (LAI) cabotegravir (CAB), which have demonstrated high efficacy in reducing HIV transmission. However, barriers persist in PrEP implementation, including provider knowledge of updated guidelines, hesitancy in discussing sexual topics with patients, logistical concerns, and disparities in access among high-risk populations, such as young men who have sex with men, racial and ethnic minorities, and individuals in the Southern United States. In this series of Curbside Consults, expert faculty review updated guidelines for patient risk assessment and PrEP eligibility; discuss interprofessional strategies for improved patient outcomes; assess the clinical evidence, availability, and appropriate use of PrEP; evaluate racial, ethnic, and geographical disparities; and present approaches to increase PrEP usage in regions with the highest rates of HIV infection.

Target Audience

The intended audience for this activity is pharmacists, family medicine physicians, internists, obstetricians/gynecologists, physician associates, nurse practitioners, and other healthcare professionals involved in the management of patients at risk for HIV.

Learning Objectives

Upon successful completion of this activity, participants should be better able to:

• Employ updated guidelines for patient risk assessment and eligibility for PrEP.
• Utilize strategies, such as interprofessional coordination of care and timely referral to HIV specialists, for improved patient outcomes.
• Communicate with patients regarding the clinical evidence, availability, and appropriate use of PrEP as well as the importance of adherence and approaches to mitigate the associated stigma.
• Recognize racial/ethnic disparities and approaches to increase the usage of PrEP in regions with the highest rates of HIV infection.

Activity Chair

Richard A. Elion, MD
Director of Clinical Research
Washington Health Institute
Clinical Professor of Medicine
George Washington University School of Medicine
Washington, DC

Faculty

Aniruddha Hazra, MD
Associate Professor, Section of Infectious Diseases and Global Health
Director, Infectious Diseases Fellowship Program
Medical Director, UCM Sexual Wellness Clinic
Director of STI Services, Chicago Center of HIV Elimination
Department of Medicine
University of Chicago
Chicago, IL

Rachel K. Scott, MD, MPH, FACOG
Scientific Director of Women's Health Research, MedStar Health Research Institute
Associate Chair for Research
MedStar Washington Hospital Center Department of Women’s & Infants’ Services
Associate Professor of Obstetrics and Gynecology, Georgetown University
Washington, DC

Samantha M. Strong, PharmD, BCACP, AAHIVP, CDCES
Clinical Director of Pharmacy, HIV/HCV Specialist
Nevada Health Centers
Las Vegas, NV

Planners/Reviewers

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
Jennifer Frederick, PharmD, BCPS
Linda A. Giarraputo, BS, PA-C

Accreditation

In support of improving patient care, Vindico Medical Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Credit Designation

This program is acceptable for 1.25 contact hour of ACPE Continuing Education Credit. The ACPE Universal Program Number is JA0006104-0000-24-056-H02-P, effective 4/30/2024. This is a knowledge-based activity, and there is no fee to attend.

Vindico Medical Education will provide pharmacist credits claimed information directly to the ACPE through CPE Monitor within 30 days.

This enduring material is approved for 1 year from the date of original release, April 30, 2024, to April 29, 2025.

How to Participate in This Activity and Obtain CE Credit

To participate in this activity, you must read the objectives, answer the polling and pretest question(s), view the content, and complete the posttest and evaluation within a maximum of 60 days of participation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 4 out of 5 of the posttest questions correctly. If a satisfactory score on the posttest is achieved, your statement of participation will be made available immediately. Click on the View Statement of Participation link and print the statement for your records. To receive Credit, you must provide your date of birth and NABP number. All Credit information will be uploaded into CPE monitor within 30 days.

Disclosures

Vindico Medical Education adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a continuing education activity, including faculty, planners, reviewers, or others, are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Relationship information is accurate at the time of content development.

Activity Chair and Faculty report the following relevant financial relationship(s)

Richard A. Elion, MD
Advisor: Gilead, Merck, ViiV
Consultant: Gilead, Merck, ViiV
Independent Research Contractor: Gilead, ViiV

Aniruddha Hazra, MD
Advisor: Abbott Technologies, Gilead, ViiV
Independent Research Contractor: Gilead

Rachel K. Scott, MD, MPH, FACOG
Advisor: ViiV
Independent Research Contractor (paid to institution): Gilead, Janssen, ViiV/GSK

Samantha M. Strong, PharmD, BCACP, AAHIVP, CDCES
Advisor: ViiV
Speaker for Ineligible Company: Gilead

Planners/Reviewers report the following relevant financial relationship(s)

Ronald A. Codario, MD, EMBA, FACP, FNLA, RPVI, CHCP
No relevant financial relationships to disclose.

Jennifer Frederick, PharmD, BCPS
No relevant financial relationships to disclose.

Linda Giarraputo, BS, PA-C
No relevant financial relationships to disclose.

Vindico Medical Education Staff

No relevant financial relationships to disclose.

Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Unlabeled and Investigational Usage

The audience is advised that this continuing education activity may contain references to unlabeled uses of FDA-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non–FDA-approved or investigational use of products/devices.

ADA Compliance

In compliance with the Americans with Disabilities Act of 1990, we will make all reasonable efforts to accommodate persons with disabilities. A text-based transcript of this lecture is available upon request. Requests should include the activity title and emailed to CME@VindicoCME.com. Requests will be honored within 3 to 5 business days.

Copyright Statement

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